| Date | Day | Time | Location | Opponent | Results |
| 8/20/2021 | Friday | 5:00/7:00 | Tiger Stadium | Longview (Scrimmage) | |
| 8/27/2021 | Friday | 7:00 | Tiger Stadium | John Tyler | W 24-10 |
| 9/3/2021 | Friday | 7:30 | Arkansas High Cancelled | Arkansas High | |
| 9/9/2021 | Thursday | 7:30 | Forney | Forney | W 34-13 |
| 9/17/2021 | Friday | Open | |||
| 9/24/2021 | Friday | 7:30 | Tiger Stadium **HOMECOMING** | MT. Pleasant | W 44-13 |
| 10/1/2021 | Friday | 7:30 | Hallsville | Hallsville | W 37-24 |
| 10/8/2021 | Friday | 7:30 | Tiger Stadium | Marshall | W 27-12 |
| 10/15/2021 | Friday | 7:30 | Pine Tree | Pine Tree | W 38-0 |
| 10/22/2021 | Friday | 7:30 | Tiger Stadium *Senior Night*  |
Jacksonville | |
| 10/29/2021 | Friday | 7:30 | Tiger Stadium *Senior Night * | Nacogdoches | |
| 11/5/2021 | Friday | 7:30 | Whitehouse | Whitehouse | |
| Date | Day | Time | Location | Opponent | Results |
| 9/17/2020 | Thursday | TBD | Lobo Stadium- Longview | Longview (Scrimmage) | |
| 9/24/2020 | Thursday | 7:00 | Rose Stadium | John Tyler | W 41-21 |
| 10/2/2020 | Friday | 7:30 | Tiger Stadium | Denison | W 24-3 |
| 10/9/2020 | Friday | 7:30 | Tiger Stadium **Homecoming** | Forney | W 49-10 |
| 10/16/2020 | Friday | 7:30 | Open | ||
| 10/23/2020 | Friday | 7:30 | Mt Pleasant - Sam Parker Field | Mt. Pleasant | W 42-24 |
| 10/30/2020 | Friday | 7:30 | Tiger Stadium *FTB/SPMED Senior Night* | Hallsville | W 56-17 |
| 11/6/2020 | Friday | 7:30 | Marshall - Maverick Stadium | Marshall | W 28-0 |
| 11/13/2020 | Friday | 7:30 | Tiger Stadium *Band Senior Night* | Pine Tree | W 44-0 |
| 11/20/2020 | Friday | 7:30 | Jacksonville - The Tomato Bowl | Jacksonville | W 52-23 |
| 11/27/2020 | Friday | 7:30 | Nacogdoches - Dragon Stadium | Nacogdoches | W 21-17 |
| 12/4/2020 | Friday | 7:30 | Tiger Stadium *Cheer/LDRSHP Senior Night* | Whitehouse | W 51-21 |
| 12/11/2020 | Friday | 7:30 | at Tiger Stadium |
Lake Creek | W 37-7 |
| 12/18/2020 | Friday | 7:00 | at Stephen F. Austin |
Crosby | L 42-62 |